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Osteocytes play an important role in experimental periodontitis in healthy and diabetic mice through expression of RANKL.

Dana T GravesAhmed AlshababMayra Laino AlbieroMarcelo MattosJôice Dias CorrêaShanshan ChenYang Yang
Published in: Journal of clinical periodontology (2018)
This study demonstrates for the first time the essential role of osteocytes in bacteria-induced periodontal bone loss and in diabetes-enhanced periodontitis.
Keyphrases
  • bone loss
  • type diabetes
  • poor prognosis
  • cardiovascular disease
  • high glucose
  • diabetic rats
  • glycemic control
  • oxidative stress
  • immune response
  • metabolic syndrome
  • long non coding rna
  • skeletal muscle