Frame-shifted proteins of a given gene are unlikely to retain the same function.

Published in: RNA (New York, N.Y.) (2020)

In a recently published paper, Huang and coworkers claim that proteins translated in different reading frames from the same mRNA can have similar functions. This conclusion is possibly incorrect due to the possibility that the wild-type protein could still be expressed.

Keyphrases

wild type
binding protein
genome wide
working memory
copy number
protein protein
dna methylation