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Alexander S Mankin

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 20

Top Venues

Nature communications

Nature chemical biology

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Moscow State University (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Moscow State University

Russia

PHD

Publications

Kyle Mangano, Dorota Klepacki, Irueosa Ohanmu, Chetana Baliga, Weiping Huang, Alexandra Brakel, Andor Krizsan, Yury S Polikanov, Ralf Hoffmann, Nora Vazquez-Laslop, Alexander S Mankin
Inhibition of translation termination by the antimicrobial peptide Drosocin. Nature chemical biology (2023)
Kornelia J Skowron, Chetana Baliga, Tatum Johnson, Kyle M Kremiller, Alexandra Castroverde, Trevor T Dean, A'Lester C Allen, Ana M Lopez-Hernandez, Elena V Aleksandrova, Dorota Klepacki, Alexander S Mankin, Yury S Polikanov, Terry W Moore
Structure-Activity Relationships of the Antimicrobial Peptide Natural Product Apidaecin. Journal of medicinal chemistry (2023)
Kaitlyn Tsai, Vanja Stojković, D John Lee, Iris D Young, Teresa Szal, Dorota Klepacki, Nora Vazquez-Laslop, Alexander S Mankin, James S Fraser, Danica Galonić Fujimori
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature structural & molecular biology 29 (2) (2022)
Yan Zhang, Nikolay A Aleksashin, Dorota Klepacki, Caleb Anderson, Nora Vazquez-Laslop, Carol A Gross, Alexander S Mankin
The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation. Proceedings of the National Academy of Sciences of the United States of America 119 (4) (2022)
Kyle Mangano, James Marks, Dorota Klepacki, Chayan Kumar Saha, Gemma C Atkinson, Nora Vazquez-Laslop, Alexander S Mankin
Context-based sensing of orthosomycin antibiotics by the translating ribosome. Nature chemical biology 18 (11) (2022)
Matthew J Mitcheltree, Amarnath Pisipati, Egor A Syroegin, Katherine J Silvestre, Dorota Klepacki, Jeremy D Mason, Daniel W Terwilliger, Giambattista Testolin, Aditya R Pote, Kelvin J Y Wu, Richard Porter Ladley, Kelly Chatman, Alexander S Mankin, Yury S Polikanov, Andrew G Myers
A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature 599 (7885) (2021)
Maxim S Svetlov, Timm O Koller, Sezen Meydan, Vaishnavi Shankar, Dorota Klepacki, Norbert Polacek, Nicholas R Guydosh, Nora Vazquez-Laslop, Daniel N Wilson, Alexander S Mankin
Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nature communications 12 (1) (2021)
Chetana Baliga, Tyler J Brown, Tanja Florin, Sarah Colon, Vallari Shah, Kornelia J Skowron, Amira Kefi, Teresa Szal, Dorota Klepacki, Terry W Moore, Nora Vazquez-Laslop, Alexander S Mankin
Charting the sequence-activity landscape of peptide inhibitors of translation termination. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Maxim S Svetlov, Egor A Syroegin, Elena V Aleksandrova, Gemma Catherine Atkinson, Steven T Gregory, Alexander S Mankin, Yury S Polikanov
Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nature chemical biology 17 (4) (2021)
Bertrand Beckert, Elodie C Leroy, Shanmugapriya Sothiselvam, Lars V Bock, Maxim S Svetlov, Michael Graf, Stefan Arenz, Maha Abdelshahid, Britta Seip, Helmut Grubmüller, Alexander S Mankin, C Axel Innis, Nora Vazquez-Laslop, Daniel N Wilson
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nature communications 12 (1) (2021)
Nikolay A Aleksashin, Teresa Szal, Anne E d'Aquino, Michael C Jewett, Nora Vazquez-Laslop, Alexander S Mankin
A fully orthogonal system for protein synthesis in bacterial cells. Nature communications 11 (1) (2020)
Alexander S Mankin
Frame-shifted proteins of a given gene are unlikely to retain the same function. RNA (New York, N.Y.) 26 (10) (2020)
Maxim S Svetlov, Sophie Cohen, Nada Alsuhebany, Nora Vazquez-Laslop, Alexander S Mankin
A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria. Proceedings of the National Academy of Sciences of the United States of America 117 (4) (2020)
Kyle Mangano, Tanja Florin, Xinhao Shao, Dorota Klepacki, Irina Chelysheva, Zoya Ignatova, Yu Gao, Alexander S Mankin, Nora Vazquez-Laslop
Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria. eLife 9 (2020)
Shijie Huang, Nikolay A Aleksashin, Anna B Loveland, Dorota Klepacki, Kaspar Reier, Amira Kefi, Teresa Szal, Jaanus Remme, Luc Jaeger, Nora Vazquez-Laslop, Andrei A Korostelev, Alexander S Mankin
Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nature communications 11 (1) (2020)
Erik D Carlson, Anne E d'Aquino, Do Soon Kim, Emily M Fulk, Kim Hoang, Teresa Szal, Alexander S Mankin, Michael C Jewett
Engineered ribosomes with tethered subunits for expanding biological function. Nature communications 10 (1) (2019)
Nikolay A Aleksashin, Margus Leppik, Adam J Hockenberry, Dorota Klepacki, Nora Vazquez-Laslop, Michael C Jewett, Jaanus Remme, Alexander S Mankin
Assembly and functionality of the ribosome with tethered subunits. Nature communications 10 (1) (2019)
Junhong Choi, James Marks, Jingji Zhang, Dong-Hua Chen, Jinfan Wang, Nora Vazquez-Laslop, Alexander S Mankin, Joseph D Puglisi
Dynamics of the context-specific translation arrest by chloramphenicol and linezolid. Nature chemical biology 16 (3) (2019)
Tanja Florin, Cristina Maracci, Michael Graf, Prajwal Karki, Dorota Klepacki, Otto Berninghausen, Roland Beckmann, Nora Vazquez-Laslop, Daniel N Wilson, Marina V Rodnina, Alexander S Mankin
An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. Nature structural & molecular biology 24 (9) (2017)
Maxim S Svetlov, Nora Vázquez-Laslop, Alexander S Mankin
Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. Proceedings of the National Academy of Sciences of the United States of America 114 (52) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alexander S Mankin