Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation.
Piero L OlliaroMax GroglMarina BoniEdgar M CarvalhoHouda ChebliMamoudou CisseErmias DiroGláucia Fernandes CotaAstrid C ErberEndalamaw GadisaFarhad HandjaniAli KhamesipourAlejandro Llanos-CuentasLiliana López CarvajalLise GroutBadre Eddine LmimouniMourad MokniMohammad Sami NahzatAfif Ben SalahYusuf OzbelJuan Miguel PascaleNidia Rizzo MolinaJoelle RodeGustavo RomeroJosé Antonio Ruiz-PostigoNancy Gore SaraviaJaime SotoSoner UzunVahid MashayekhiIvan Dario VélezFlorian VogtOlga ZerpaByron AranaPublished in: PLoS neglected tropical diseases (2018)
The consensus reached allows standardization of future clinical research across OWCL and NWCL sites. We encourage CL researchers to adopt and adapt as required the proposed parameters and outcomes in their future trials and provide feedback on their experience. The expertise afforded between the two sets of clinical sites provides the basis for a powerful consortium with potential for extensive, standardized assessment of interventions for CL and faster approval of candidate treatments.