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Comparison of lixisenatide in combination with basal insulin vs other insulin regimens for the treatment of patients with type 2 diabetes inadequately controlled by basal insulin: Systematic review, network meta-analysis and cost-effectiveness analysis.

Peng MenShuli QuWenting LuoChaoyun LiSuo-di Zhai
Published in: Diabetes, obesity & metabolism (2019)
Lixisenatide plus BI shows a similar HbA1c reduction compared with insulin regimens, accompanied by lower risk of hypoglycaemia and greater body weight reduction. It is a cost-effective treatment alternative for patients with T2DM inadequately controlled by BI in China.
Keyphrases
  • systematic review
  • type diabetes
  • glycemic control
  • body weight
  • meta analyses
  • randomized controlled trial
  • combination therapy
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • weight loss