Dynamic Changes in Circulating Methylated Markers in Response to Antitumor Therapy of Rectal Cancer.
Anastasia A PonomaryovaElena Yu RykovaAnastasia I SolovyovaAnna S TarasovaDmitry N KostromitskyAlexey Yu DobrodeevSergey A AfanasievNadezhda V CherdyntsevaPublished in: Journal of gastrointestinal cancer (2024)
The results indicate that SEPTIN9, IKZF1, and LINE-1 methylation levels in the csb-cfDNA are potential markers of the effectiveness of antitumor therapy and early detection of relapse in RC patients.
Keyphrases
- rectal cancer
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- systematic review
- acute lymphoblastic leukemia
- prognostic factors
- dna methylation
- stem cells
- locally advanced
- genome wide
- gene expression
- radiation therapy
- patient reported outcomes
- risk assessment