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Treatment outcomes of cutaneous leishmaniasis due to Leishmania aethiopica: A systematic review and meta-analysis.

Abebaw Yeshambel AlemuLemma DersehMirgissa KabaEndalamaw GadisaKassahun Alemu
Published in: PloS one (2023)
The pooled proportion of cure is low with antimonial monotherapy. Despite limited evidence, combination therapies are a promising treatment option for all clinical phenotypes of CL caused by L. aethiopica. Future high-quality randomized control trials are needed to identify effective monotherapies and evaluate the effectiveness of combination therapies.
Keyphrases
  • open label
  • phase iii
  • combination therapy
  • randomized controlled trial
  • double blind
  • systematic review
  • placebo controlled
  • clinical trial
  • phase ii
  • study protocol
  • replacement therapy
  • smoking cessation