A Phase Ib Clinical Trial of Metformin and Chloroquine in Patients with IDH1-Mutated Solid Tumors.
Mohammed KhurshedRemco J MolenaarMyra E van LindeRon A A MathotEduard A StruysJ Tom van WezelCornelis J F van NoordenHeinz-Josef KlümpenJudith V M G BovéeJohanna W WilminkPublished in: Cancers (2021)
Treatment of advanced IDH1-mutated solid tumors with metformin and chloroquine was well tolerated but did not induce a clinical response in this phase Ib clinical trial.