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The Effects of the 3-OH Group of Kaempferol on Interfollicular Epidermal Stem Cell Fate.

Je Byeong ChaeHye-Ryung ChoiJung-Won ShinJung-Im NaChang-Hun HuhKyoung-Chan Park
Published in: Annals of dermatology (2018)
Our findings indicated that kaempferol can increase the proliferative potential of basal epidermal cells by modulating the basement membrane. In other words, kaempferol can affect the fate of interfollicular epidermal stem cells by increasing the expression of both integrins α6 and β1. These effects, in particular, might be ascribed to the 3-OH group of kaempferol.
Keyphrases
  • stem cells
  • cell fate
  • wound healing
  • induced apoptosis
  • poor prognosis
  • signaling pathway
  • cell cycle arrest
  • oxidative stress
  • cell therapy
  • cell proliferation
  • long non coding rna
  • human health