Etrolizumab as an induction and maintenance therapy for ulcerative colitis: A systematic review and meta-analysis of randomized controlled trials.

Othman SalehMohamed T AbuelazmIslam MohamedAlaa RamadanMohammad AssafAhmad AlzoubiMajd M AlBarakatBasel Abdelazeem

Published in: JGH open : an open access journal of gastroenterology and hepatology (2024)

Etrolizumab shows its effectiveness as both an induction and maintenance therapy for moderate or severe UC. The findings demonstrate its positive impact on clinical, endoscopic, and histologic remission rates. Regarding safety, other than any side effects, etrolizumab showed a good safety than a placebo.

Keyphrases

ulcerative colitis
systematic review
randomized controlled trial
ultrasound guided
high intensity
early onset
clinical trial
rheumatoid arthritis
double blind
phase iii
open label
placebo controlled