The miR151 and miR5100 Transfected Bone Marrow Stromal Cells Increase Myoblast Fusion in IGFBP2 Dependent Manner.

Bartosz MierzejewskiZuzanna MichalskaDaniel JackowskiWładysława StreminskaKatarzyna Janczyk-IlachMarta KoblowskaRoksana Iwanicka-NowickaAgnieszka GromadkaMaria Anna CiemerychEdyta Brzoska

Published in: Stem cell reviews and reports (2022)

Mouse BMSCs did not present naïve myogenic potential but secreted proteins could impact myogenic cell differentiation. miR151 and miR5100 transfection changed BMSC migration and IGFBP2 and MMP12 expression in BMSCs. miR151 and miR5100 transfected BMSCs increased myoblast fusion in vitro.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
poor prognosis
bone marrow
mesenchymal stem cells
binding protein