Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults.

Ravi V Shah Jiawei Zhong Lucas Massier Kahraman Tanriverdi Shih-Jen HwangJeffrey HaesslerMatthew Nayor Shilin Zhao Andrew S Perry John T WilkinsAladdin H ShadyabJo Ann E Manson Lisa Warsinger Martin Daniel Levy Charles Kooperberg Jane E Freedman Mikael Rydén Venkatesh L Murthy

Published in: Circulation. Genomic and precision medicine (2024)

A multifaceted discovery effort uniting proteomics, underlying clinical susceptibility phenotypes, and tissue expression patterns may uncover potentially novel functional biomarkers of early diabetes susceptibility in young adults for future mechanistic evaluation.

Keyphrases

young adults
type diabetes
cardiovascular disease
mass spectrometry
glycemic control
poor prognosis
small molecule
high throughput
cancer therapy
childhood cancer
current status
metabolic syndrome
binding protein
drug delivery
insulin resistance
clinical evaluation