Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial.
Craig M DaleLouise RoseSarah CarboneRuxandra PintoOrla M SmithLisa D BurryEddy FanAndre Carlos Kajdacsy-Balla AmaralVictoria A McCredieDamon C ScalesBrian H CuthbertsonPublished in: Intensive care medicine (2021)
Among mechanically ventilated ICU patients, no benefit was observed for de-adoption of chlorhexidine and implementation of an oral care bundle on ICU mortality, IVACs, oral procedural pain, or time to extubation. The intervention may improve oral health.
Keyphrases
- end stage renal disease
- intensive care unit
- healthcare
- ejection fraction
- quality improvement
- primary care
- peritoneal dialysis
- chronic kidney disease
- randomized controlled trial
- newly diagnosed
- palliative care
- prognostic factors
- oral health
- mechanical ventilation
- study protocol
- pain management
- type diabetes
- chronic pain
- cardiovascular disease
- patient reported outcomes
- clinical trial
- spinal cord injury
- cardiac surgery
- patient reported