Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation.

Woo-Jeong ShonJae Won SongSeung Hoon OhKeon-Hee LeeHobin SeongHyun Ju YouJe Kyung SeongDong-Mi Shin

Published in: BMC medicine (2023)

Our findings suggest that the TAS1R3-mTOR-PPARγ axis in the gut links Western diet consumption with intestinal inflammation and is a potential therapeutic target for IBD.

Keyphrases

oxidative stress
south africa
physical activity
transcription factor
cell proliferation
skeletal muscle
type diabetes
insulin resistance
fatty acid
binding protein
ulcerative colitis