Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade.

Jelena KornejPetra BüttnerElke HammerBeatrice EngelmannBorislav DinovPhilipp SommerDaniela HusserGerhard HindricksUwe VölkerAndreas Bollmann

Published in: PloS one (2018)

This pilot proteomic study identified plasma protein candidates associated with electro-anatomical remodeling in AF and pointed towards an imbalance in coagulation and complement pathway, tissue remodeling and inflammation.

Keyphrases

left atrial
atrial fibrillation
mitral valve
left ventricular
oxidative stress
catheter ablation
heart failure
randomized controlled trial
study protocol
protein protein
high speed
small molecule
amino acid
binding protein