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Oral beclomethasone dipropionate is an effective treatment for immune checkpoint inhibitor induced colitis.

James L AlexanderHajir IbraheimCamellia RichardsBen ShumPolychronis PavlidisNikki HunterJulian P TeareAndrew WotherspoonAndrew FurnessSamra TurajlicLisa PickeringJames LarkinAlly SpeightSophie PapaNick Powell
Published in: Journal for immunotherapy of cancer (2022)
Topical BD represents an appealing alternative option to systemic immunosuppressive treatments to treat colonic inflammation. In this study, BD was effective and safe at inducing remission in CPI-induced colitis, which was refractory to systemic corticosteroids. Further randomized studies are needed to confirm these findings and determine the optimum dosing regimen.
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