DNA methylation dynamics in response to abiotic and pathogen stress in plants.
Heena AroraRoshan Kumar SinghShambhavi SharmaNamisha SharmaAnurag PanchalTuhin DasAshish PrasadManoj PrasadPublished in: Plant cell reports (2022)
DNA methylation is a dynamic epigenetic mechanism that plays a significant role in gene expression and also maintains chromatin stability. The process is conserved in both plants and animals, and crucial for development and stress responses. Differential DNA methylation during adverse environmental conditions or pathogen attack facilitates the selective expression of defense-related genes. Both stress-induced DNA hypomethylation and hypermethylation play beneficial roles in activating the defense response. These DNA marks may be carried to the next generation making the progenies 'primed' for abiotic and biotic stress responses. Over the recent years, rapid advancements in the area of high throughput sequencing have enabled the detection of methylation status at genome levels in several plant species. Epigenotyping offers an alternative tool to plant breeders in addition to conventional markers for the selection of the desired offspring. In this review, we briefly discuss the mechanism of DNA methylation, recent understanding of DNA methylation-mediated gene regulation during abiotic and biotic stress responses, and stress memory in plants.
Keyphrases
- dna methylation
- gene expression
- genome wide
- stress induced
- copy number
- transcription factor
- single molecule
- circulating tumor
- high throughput sequencing
- loop mediated isothermal amplification
- cell free
- poor prognosis
- type diabetes
- candida albicans
- binding protein
- high fat diet
- signaling pathway
- metabolic syndrome
- risk assessment
- oxidative stress
- climate change
- working memory
- adverse drug
- innate immune