Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination.
Leigh K HawkinsMarilyn L WarburtonJuliet TangJohn TomashekDafne Alves OliveiraOluwaseun F OgunolaJ Spencer SmithW Paul WilliamsPublished in: Toxins (2018)
Many projects have identified candidate genes for resistance to aflatoxin accumulation or Aspergillus flavus infection and growth in maize using genetic mapping, genomics, transcriptomics and/or proteomics studies. However, only a small percentage of these candidates have been validated in field conditions, and their relative contribution to resistance, if any, is unknown. This study presents a consolidated list of candidate genes identified in past studies or in-house studies, with descriptive data including genetic location, gene annotation, known protein identifiers, and associated pathway information, if known. A candidate gene pipeline to test the phenotypic effect of any maize DNA sequence on aflatoxin accumulation resistance was used in this study to determine any measurable effect on polymorphisms within or linked to the candidate gene sequences, and the results are published here.
Keyphrases
- genome wide
- copy number
- single cell
- case control
- high resolution
- cross sectional
- healthcare
- gene expression
- risk assessment
- systematic review
- drinking water
- genome wide identification
- mass spectrometry
- small molecule
- machine learning
- single molecule
- quality improvement
- artificial intelligence
- social media
- data analysis
- genetic diversity