Retrospective investigation of hereditary syndromes in patients with medulloblastoma in a single institution.

Ying WangJingchuan WuWei LiJiankang LiRaynald LiuBao YangChunde LiTao Jiang

Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2020)

Patients with SHH medulloblastoma should routinely undergo genetic testing. We propose that whole genome, whole exome sequence, or custom-designed panel-targeted exome sequencing should be performed.

Keyphrases

copy number
single cell
cross sectional
cancer therapy
dna methylation
genome wide