Safety and Efficacy of Crizotinib in Combination with Temozolomide and Radiotherapy in Patients with Newly Diagnosed Glioblastoma: Phase Ib GEINO 1402 Trial.
María Martínez-GarcíaGuillermo VelascoEstela Pineda LosadaMiguel Gil-GilFrancesc AlamedaJaume CapelladesMari Cruz Martín-SoberónIsrael López-ValeroElena Tovar AmbelPalmira ForoÁlvaro TausMontserrat ArumiAurelio Hernández-LaínJuan Manuel Sepúlveda SánchezPublished in: Cancers (2022)
The addition of crizotinib to standard RT and TMZ for newly diagnosed GBM was safe and the efficacy was encouraging, warranting prospective validation in an adequately powered, randomized controlled study.