A multi-centre randomised control trial of directly observed therapy to promote medication adherence in paediatric heart transplant recipients.
Michael O KillianSonnie MayewskiDipankar GuptaPublished in: Cardiology in the young (2024)
Medication non-adherence remains a significant challenge for adolescent heart transplant recipients. Building on the success of a pilot intervention study, herein we describe the protocol for a follow-up randomised control trial using mobile video directly observed therapy, featuring several innovations, to promote medication adherence in a multi-centre sample of adolescent heart transplant patients.
Keyphrases
- clinical trial
- heart failure
- randomized controlled trial
- study protocol
- young adults
- end stage renal disease
- open label
- mental health
- newly diagnosed
- ejection fraction
- atrial fibrillation
- double blind
- chronic kidney disease
- emergency department
- healthcare
- placebo controlled
- peritoneal dialysis
- stem cells
- type diabetes
- bone marrow
- adverse drug
- insulin resistance
- skeletal muscle