TdT expression in germ cell tumours: a possible immunohistochemical cross-reaction and diagnostic pitfall.
Marta JaconiFulvio MagniFrancesca RaimondoMaurilio PonzoniClizia ChinelloAndrew SmithIsabella PigaNicola FuscoCamillo Di BellaFabio PagniPublished in: Journal of clinical pathology (2019)
Alternatively to the pathogenetic link between TdT expression and GCTs tumourigenesis, we hypothesised the occurrence of a spurious immunohistochemical nuclear cross-reaction, a well-known phenomenon with important implications and a possible source of diagnostic pitfalls in routine practice for pathologists.