Plasma oxysterols are associated with serum lipids and dementia risk in older women.

Michelle M DunkStephen R RappKathleen M HaydenMark A EspelandRamon CasanovaJoAnn E MansonAladdin H ShadyabRobert WildIra Driscoll

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Less favorable lipid profiles were associated with higher oxysterol levels. A higher ratio of 24-OHC/27-OHC may contribute to dementia risk in APOE3 and APOE4+ carriers.

Keyphrases

mild cognitive impairment
cognitive decline
cognitive impairment
high fat diet
fatty acid
type diabetes
adipose tissue
insulin resistance