Login / Signup

Neopterin Relates to Lifetime Depression in Older Adults With HIV on Suppressive Antiretroviral Therapy.

Rowan SalonerNatalie SaviniScott L LetendreDavid J MooreJessica L Montoya
Published in: Journal of acquired immune deficiency syndromes (1999) (2022)
Neopterin was associated with lifetime MDD, but not current depressive symptoms in older PWH on suppressive ART. This may reflect a legacy of inflammation-related disruptions to amino acid metabolism and neurotransmitter synthesis, similar to prior observations. Identification of biopsychosocial and resilience factors underlying the null association between neopterin and current depression in older PWH is warranted.
Keyphrases