Comprehensive kinome NGS targeted expression profiling by KING-REX.

Giovanni CarapezzaCarlo CusiEttore RizzoLaura RaddrizzaniSebastiano Di BellaAlessio SomaschiniAntonella LeoneRosita LupiMargherita MutarelliVincenzo NigroDiego di BernardoPaolo MagniAntonella IsacchiRoberta Bosotti

Published in: BMC genomics (2019)

These results support the use of KING-REX as a rapid and cost effective kinome investigation tool in the field of kinase target identification for applications in cancer biology and other human diseases.

Keyphrases

endothelial cells
papillary thyroid
squamous cell
induced pluripotent stem cells
genome wide
pluripotent stem cells
cancer therapy
tyrosine kinase
protein kinase
gene expression
lymph node metastasis
squamous cell carcinoma
transcription factor
childhood cancer
genome wide identification