circHMGCS1-016 reshapes immune environment by sponging miR-1236-3p to regulate CD73 and GAL-8 expression in intrahepatic cholangiocarcinoma.

Ya-Ping XuZe-Ning DongSi-Wei WangYi-Min ZhengChi ZhangYing-Qun ZhouYu-Jie ZhaoYan ZhaoFeng WangRui PengMao-Chun TangDou-Sheng BaiXiao-Yong HuangChuan-Yong Guo

Published in: Journal of experimental & clinical cancer research : CR (2021)

CircHMGCS1-016 is a forceful contributor in ICC development and immune tolerance via miR-1236-3p/CD73 and GAL-8 axis. CircHMGCS1-016 can be explored as a new potential biomarker and therapeutic target for PD1-resistant ICC.

Keyphrases

poor prognosis
nk cells