TMPRSS2 Impacts Cytokine Expression in Murine Dendritic Cells.
Sandra GunneMarie SchwerdtnerMarina HenkeAnn-Kathrin SchneiderLucas KeutmannEva Böttcher-FriebertshäuserSusanne SchiffmannPublished in: Biomedicines (2023)
The effect of TMPRSS2 on pDCS and cDCs depends on the activated TLR, and TMPRSS2 seems to affect cytokine release differently in pDCs and cDCs. In cDCs, TMPRSS2 seems to suppress cytokine release, whereas in pDCS TMPRSS2 possibly mediates cytokine release.