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Hepatic Acyl CoA Oxidase1 Inhibition Modifies Brain Lipids and Electrical Properties of Dentate Gyrus.

Shahrbanoo RafieiFariba KhodagholiHamid Gholami PourbadieLeila DargahiFereshteh Motamedi
Published in: Basic and clinical neuroscience (2023)
The results indicated that systemic inhibition of ACOX1 causes hypo-excitability of neuronal cells. These results provide new evidence on the involvement of peroxisome function and hepatic ACOX1 activity in brain fatty acid profile and the electrophysiological properties of dentate gyrus cells.
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