Randomized phase II study of valproic acid in combination with bevacizumab and oxaliplatin/fluoropyrimidine regimens in patients with RAS-mutated metastatic colorectal cancer: the REVOLUTION study protocol.

Antonio AvalloneMaria Carmela PiccirilloElena Di GennaroCarmela RomanoFilomena CalabreseMaria Serena RocaFabiana TatangeloVincenza GranataAntonio CassataErnesta CavalcantiNicola MaureaPiera MaiolinoLucrezia SilvestroAlfonso De StefanoFrancesco GiulianiGerardo RosatiEmiliano TamburiniPasquale ApreaValeria VicarioAnna NappiCarlo VitaglianoRossana CasarettiAlessandra LeoneAntonella PetrilloGerardo BottiPaolo DelrioFrancesco IzzoFrancesco PerroneAlfredo Budillon

Published in: Therapeutic advances in medical oncology (2020)

EudraCT: 2018-001414-15; ClinicalTrials.gov identifier: NCT04310176.

Keyphrases

metastatic colorectal cancer
phase ii study
open label
study protocol
placebo controlled
wild type
double blind
phase iii
phase ii
clinical trial
randomized controlled trial
squamous cell carcinoma
locally advanced