Dysregulation of RNA interference components in COVID-19 patients.

Seyyed Reza MousaviMaryam Sadat SajjadiFarinaz KhosravianSara FeizbakhshanSharareh SalmanizadehZahra Taherian EsfahaniFaeze Ahmadi BeniAmeneh ArabMohammad KazemiKiana ShahzamaniRamin SamiMajid HosseinzadehMansoor SalehiHajie Lotfi

Published in: BMC research notes (2021)

Our findings demonstrated that the expression of Dicer, Drosha, and Ago2 was statistically altered in COVID-19 patients compared to healthy subjects. Ultimately, the RNA interference mechanism as a crucial antiviral defense system was suggested to be dysregulated in COVID-19 patients.

Keyphrases

sars cov
poor prognosis
nucleic acid