Prognostic Significance of DNA Methylation Profiles at MRI Enhancing Tumor Recurrence: a Report from the EORTC 26091 TAVAREC Trial.
Kaspar DraaismaC Mircea S TesileanuIris de HeerMartin KleinMarion SmitsJaap C ReijneveldPaul M J ClementFilip Yves Francine De VosAntje WickPaul J MulhollandMartin J B TaphoornMichael WellerOlivier Louis ChinotJohan M KrosTina VerschuereCorneel CoensVassilis GolfinopoulosThierry GorliaAhmed IdbaihPierre A J T RobeMartin J Van Den BentPim J FrenchPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
DNA methylome Heidelberg classification at time of diagnosis is no longer of prognostic value at the time of enhancing recurrence. CDKN2A/B deletion status was predictive of survival from progression of IDH-mutated tumors.
Keyphrases
- free survival
- dna methylation
- magnetic resonance imaging
- machine learning
- deep learning
- circulating tumor
- wild type
- contrast enhanced
- study protocol
- gene expression
- genome wide
- clinical trial
- phase iii
- single molecule
- low grade
- cell free
- phase ii
- computed tomography
- randomized controlled trial
- diffusion weighted imaging
- magnetic resonance
- nucleic acid
- double blind