Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study.
Elizabeth G HollidayThomas LillicrapTimothy KleinigPhilip M C ChoiJane MaguireAndrew BivardLisa F LinczMonica Anne Hamilton-BruceSushma R RaoMarten F SnelPaul J TrimLongting LinMark W ParsonsBradford B WorrallSimon A KoblarJohn Richard AttiaChris LeviPublished in: BMJ open (2020)
Patients, or relatives when patients could not consent, provide written informed consent to participate. This study received approval from the Hunter New England Local Health District Human Research Ethics Committee (reference 14/10/15/4.02). Findings will be disseminated via peer-reviewed publications and conference presentations.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- public health
- chronic kidney disease
- healthcare
- peritoneal dialysis
- randomized controlled trial
- mental health
- skeletal muscle
- pulmonary embolism
- machine learning
- metabolic syndrome
- liver failure
- coronary artery disease
- acute coronary syndrome
- acute ischemic stroke
- climate change
- cancer therapy
- drug delivery
- patient reported outcomes
- atrial fibrillation
- big data
- left ventricular
- drug induced
- weight loss
- cerebral ischemia