Immunogenicity evaluation of recombinant Lactobacillus casei W56 expressing bovine viral diarrhea virus E2 protein in conjunction with cholera toxin B subunit as an adjuvant.

Shuo JiaXinning HuangHua LiDianzhong ZhengLi WangXinyuan QiaoYanping JiangWen CuiLijie TangYijing LiYigang Xu

Published in: Microbial cell factories (2020)

The genetically engineered Lactobacillus vaccine constructed in this study is immunogenic in mice and can induce mucosal, humoral, and cellular immune responses, providing effective anti-BVDV immune protection. It thus represents a promising strategy for vaccine development against BVDV.

Keyphrases

immune response
escherichia coli
sars cov
early stage
type diabetes
dendritic cells
lactic acid
protein protein
adipose tissue
binding protein
ulcerative colitis
irritable bowel syndrome
wild type
high fat diet induced
small molecule
insulin resistance