Clinical efficacy on glycemic control and safety of mesenchymal stem cells in patients with diabetes mellitus: Systematic review and meta-analysis of RCT data.

Jingjing HeDesheng KongZhifen YangRuiyun GuoAsiamah Ernest AmponsahBaofeng FengXiaolin ZhangWei ZhangAijing LiuJun Ma Timothy O'BrienHuixian Cui

Published in: PloS one (2021)

This meta-analysis revealed MSCs therapy may be an effective and safe intervention in subjects with diabetes. However, due to the limited studies, a number of high-quality as well as large-scale RCTs should be performed to confirm these conclusions.

Keyphrases

glycemic control
mesenchymal stem cells
case control
type diabetes
systematic review
umbilical cord
blood glucose
randomized controlled trial
weight loss
meta analyses
bone marrow
cell therapy
insulin resistance
electronic health record
single cell
big data
cardiovascular disease
machine learning
skeletal muscle