PAR1 regulation of CXCL1 expression and neutrophil recruitment to the lung in mice infected with influenza A virus.

Saravanan SubramaniamKohei TatsumiClare M SchmedesGrant J EgnatzAlyson C AuriemmaVanthana BharathiTracy StokolMelinda A BeckJohn H GriffinJoseph S PalumboNigel Mackman

Published in: Journal of thrombosis and haemostasis : JTH (2021)

These results indicate that PAR1 expression by different cell types and activation by different proteases modulates the immune response during IAV infection.

Keyphrases

poor prognosis
immune response
single cell
binding protein
cell therapy
long non coding rna
stem cells
dendritic cells
adipose tissue
toll like receptor
bone marrow
wild type