GPR35 mediates lodoxamide-induced migration inhibitory response but not CXCL17-induced migration stimulatory response in THP-1 cells; is GPR35 a receptor for CXCL17?

Soo-Jin ParkSeung-Jin LeeSo-Yeon NamDong-Soon Im

Published in: British journal of pharmacology (2017)

The present findings suggest that GPR35 functions as a migration inhibitory receptor, but CXCL17-stimulated migration of THP-1 cells is not dependent on GPR35.

Keyphrases

induced apoptosis
fatty acid
cell cycle arrest
high glucose
diabetic rats
oxidative stress
endoplasmic reticulum stress
cell death
drug induced