Pacybara: accurate long-read sequencing for barcoded mutagenized allelic libraries.

Jochen WeileGabrielle FerraGabriel BoyleSriram PendyalaClara AmorosiChiann-Ling C YehAtina G CoteNishka KishoreDaniel TabetWarren van LoggerenbergAshyad RayhanDouglas M FowlerMaitreya J Dunham Frederick P Roth

Published in: Bioinformatics (Oxford, England) (2024)

Pacybara, freely available at https://github.com/rothlab/pacybara, is implemented using R, Python, and bash for Linux. It runs on GNU/Linux HPC clusters via Slurm, PBS, or GridEngine schedulers. A single-machine simplex version is also available.

Keyphrases

psychometric properties
single cell
single molecule
deep learning
high resolution
mass spectrometry
high throughput sequencing