The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.
Estelle Ayme-DietrichRoland LawsonFrancine CôtéClaudia de TapiaSylvia Da SilvaClaudine EbelBéatrice HechlerChristian GachetJérome GuyonnetHélène RouillardJordane StoltzEmily QuentinSophie BanasFrançois DaubeufNelly FrossardBernard GasserJean-Philippe MazzucotelliOlivier HermineLuc MaroteauxLaurent MonassierPublished in: British journal of pharmacology (2017)
BM-derived endothelial progenitor cells make a crucial contribution to the remodelling of mitral valve tissue. Our data describe a new and important mechanism underlying human VHD.