Correlation between double-stranded DNA and acute urticaria.

Yuanyuan LiZhuo LiJiayi LuGuangbo QuQin QinChang ZhangYuanming BaiDaiyue WangSihan LuoBao LiYang HanWeiwei ChenQi ZhenLiangdan Sun

Published in: International journal of dermatology (2024)

We demonstrated that serum dsDNA levels are elevated in acute urticaria and are influenced by climatic factors such as temperature, ultraviolet index, and season. We also found that elevated dsDNA promotes the expression of AIM2-related factors and type I interferons. This study generates new hypotheses regarding the pathogenesis of acute urticaria and suggests novel therapeutic targets.

Keyphrases

liver failure
respiratory failure
drug induced
aortic dissection
poor prognosis
hepatitis b virus
binding protein
circulating tumor
cell free
acute respiratory distress syndrome
circulating tumor cells