Association between misoprostol and non-steroidal anti-inflammatory drug-induced kidney injury: a systematic review and meta-analysis.

Satoru Mitsuboshi Kazumasa KotakeTakeru TakahashiKoji SatoToshiyuki Sakamaki

Published in: British journal of clinical pharmacology (2023)

There is limited evidence that misoprostol reduces the risk of NSAID-induced kidney injury. Misoprostol possibly contributes to reducing the risk of kidney injury associated with chronic NSAID use. The findings of this meta-analysis suggest further high-quality clinical trials are warranted.

Keyphrases

drug induced
liver injury
systematic review
clinical trial
anti inflammatory
adverse drug
meta analyses
randomized controlled trial
high glucose
phase ii
endothelial cells
stress induced