LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.

Haihai LiangTong YuYue HanHua JiangChengyu WangTianyi YouXiaoguang ZhaoHuitong ShanRui YangLida YangHongli ShanYunyan Gu

Published in: Molecular cancer (2018)

Taken together, the results from our study highlight a role for the PTAR-miR-101-ZEB1 axis in OvCa, which offers novel strategies for the prevention of metastasis in OvCa.

Keyphrases

long non coding rna
epithelial mesenchymal transition
poor prognosis
long noncoding rna
cell proliferation
high grade
cell migration
signaling pathway
transcription factor
dna binding