Biogenic synthesis of gold nanoparticles using Argemone mexicana L. and their cytotoxic and genotoxic effects on human colon cancer cell line (HCT-15).

Kailas D DatkhileSatish R PatilPratik P DurgawaleMadhavi N PatilDilip D HingeNilam J JagdaleVinit N DeshmukhAshwini L More

Published in: Journal, genetic engineering & biotechnology (2021)

The AM-AuNPs may exert antiproliferative and genotoxic effects on HCT-15 cells by cell growth suppression and induction of apoptosis mediated by activation of p53 and caspase-3 genes.

Keyphrases

cell cycle arrest
cell death
gold nanoparticles
pi k akt
induced apoptosis
endothelial cells
endoplasmic reticulum stress
signaling pathway
induced pluripotent stem cells
oxidative stress
pluripotent stem cells
reduced graphene oxide
cell proliferation