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Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study.

Hyun Jung LimMan-Hoon HanEun Hye LeeDong Hyuk EunJun Young KimWeon Ju LeeSeok-Jong LeeDo Won KimTae-In ParkSang-Hyun KimYong Hyun Jang
Published in: Annals of dermatology (2019)
The results suggest that IL-12 secreted from dermal inflammatory cells might be one of the important factors associated with the formation of psoriasiform features in chronic AD. However, further studies are required to better define the specific role of IL-12.
Keyphrases
  • atopic dermatitis
  • induced apoptosis
  • poor prognosis
  • oxidative stress
  • cell cycle arrest
  • wound healing
  • endoplasmic reticulum stress
  • signaling pathway
  • binding protein
  • cell death
  • cell proliferation