Transcutaneous electrical cranial-auricular acupoint stimulation versus escitalopram for mild-to-moderate depression: an assessor-blinded, randomized, non-inferiority trial.

Zhang-Jin ZhangShui-Yan ZhangXin-Jing YangZong-Shi QinFeng-Quan XuGui-Xing JinXiao-Bing HouYong LiuJi-Fu CaiHai-Bing XiaoYat Kwan WongYu ZhengLei ShiJin-Niu ZhangYuan-Yuan ZhaoXue XiaoLiu-Lu ZhangYue JiaoYu WangJia-Kai HeGuo-Bing ChenPei-Jing Rong

Published in: Psychiatry and clinical neurosciences (2022)

TECAS was comparable to escitalopram in improving depression and related symptoms, with high acceptability, better safety profile, and particular efficacy in reducing trauma-associated depression. It could serve an effective portable therapy for mild-to-moderate depression. This article is protected by copyright. All rights reserved.

Keyphrases

depressive symptoms
sleep quality
major depressive disorder
phase iii
clinical trial
phase ii
placebo controlled
randomized controlled trial
bipolar disorder
low cost
trauma patients