The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine.
Louis D FioreMary T BrophySara TurekValmeek KudesiaNithya RamnathColleen ShannonRyan FergusonSaiju PyarajanMelissa A FioreJohn HornbergerPhilip LavoriPublished in: Biomarkers in cancer (2016)
The Department of Veterans Affairs (VA) recognized the need to balance patient-centered care with responsible creation of generalizable knowledge on the effectiveness of molecular medicine tools. Embracing the principles of the rapid learning health-care system, a new clinical program called the Precision Oncology Program (POP) was created in New England. The POP integrates generalized knowledge about molecular medicine in cancer with a database of observations from previously treated veterans. The program assures access to modern genomic oncology practice in the veterans affairs (VA), removes disparities of access across the VA network of clinical centers, disseminates the products of learning that are generalizable to non-VA settings, and systematically presents opportunities for patients to participate in clinical trials of targeted therapeutics.
Keyphrases
- quality improvement
- palliative care
- healthcare
- papillary thyroid
- clinical trial
- end stage renal disease
- newly diagnosed
- systematic review
- randomized controlled trial
- squamous cell
- primary care
- chronic kidney disease
- ejection fraction
- single molecule
- dna methylation
- prognostic factors
- emergency department
- patient reported outcomes
- cancer therapy
- small molecule
- pain management
- affordable care act
- peritoneal dialysis
- network analysis
- chronic pain
- quantum dots
- phase iii