68Ga-FAPI-04 PET/CT and 18F-FDG PET/CT in Metastatic Papillary Renal Cell Cancer.
Caner CivanEmine Goknur IsikSeyfullah KaradoganYasemin SanliSerkan KuyumcuPublished in: Clinical nuclear medicine (2023)
Papillary renal cell cancer is a rare malignancy with limited treatment options in the advanced stage of the disease. We present the case of a 62-year-old man with progressive left-sided papillary renal cell carcinoma who underwent 68Ga-FAPI (fibroblast activated protein inhibitor)-04 and 18F-FDG PET/CT imaging. 68Ga-FAPI-04 PET/CT demonstrated variable FAP expression in all metastatic lesions detected by 18F-FDG PET/CT, including multiple lymph nodes, bone, and thyroid. This case highlights that FAP-targeted imaging can be a promising modality for diagnostic and theranostic use in papillary renal cell carcinoma.
Keyphrases
- pet ct
- renal cell carcinoma
- clear cell
- papillary thyroid
- lymph node
- squamous cell carcinoma
- positron emission tomography
- high resolution
- single cell
- small cell lung cancer
- squamous cell
- cell therapy
- multiple sclerosis
- photodynamic therapy
- poor prognosis
- fluorescence imaging
- stem cells
- lymph node metastasis
- cancer therapy
- drug delivery
- young adults
- mass spectrometry
- bone marrow
- body composition
- sentinel lymph node
- locally advanced