Maternal circulating exosomal miR-185-5p levels as a predictive biomarker in patients with recurrent pregnancy loss.

Yujing XiongZheng FangJie DongShuqiang ChenJiaqin MaoWanlin ZhangLi HaiJing ZhouXiaohong Wang

Published in: Journal of assisted reproduction and genetics (2023)

The current study, for the first time, successfully constructed the correlation between maternal circulating exosomal miR-185-5p expression pattern and RPL, which may be involved in the pathogenesis of RPL by downregulating the VEGFA of dNK cells and perturbing angiogenesis at the maternal-fetal interface.

Keyphrases

pregnancy outcomes
birth weight
induced apoptosis
poor prognosis
pregnant women
cell cycle arrest
preterm birth
endoplasmic reticulum stress
binding protein