Bivalent mRNA vaccine effectiveness against SARS-CoV-2 variants of concern.

Monika KumariShih-Chieh SuKang-Hao LiangHsiu-Ting LinYu-Feng LuKai-Chi ChenWan-Yu ChenHan-Chung Wu

Published in: Journal of biomedical science (2023)

Our results show that combining two mRNA sequences may be an effective way to develop a broadly protective SARS-CoV-2 vaccine against a wide range of variant types. Importantly, we provide the optimal combination regimen and propose a strategy that may prove useful in combating future VOCs.

Keyphrases

sars cov
respiratory syndrome coronavirus
randomized controlled trial
systematic review
binding protein
copy number
current status
gene expression
genome wide