Metabolomics of IgE-Mediated Food Allergy and Oral Immunotherapy Outcomes based on Metabolomic Profiling.

Yamini V Virkud Jennifer N Styles Rachel S Kelly Sarita Ulhas Patil Bert Ruiter Neal P Smith Andrew T Chan Craig E Wheelock Juan C Celedón Augusto A Litonjua Supinda Bunyavanich Scott T Weiss Erin S Baker Jessica A Lasky-Su Wayne G Shreffler

Published in: medRxiv : the preprint server for health sciences (2024)

This is the first study of plasma metabolomic profiles of responses to OIT in individuals with IgE-mediated food allergy. Identification of immunomodulatory metabolites in allergic tolerance may help identify mechanisms of tolerance and guide future therapeutic development.

Keyphrases

mass spectrometry
ms ms
current status
type diabetes
metabolic syndrome
insulin resistance