Pharmacovigilance of nephrotoxic drugs in neonates: the Pottel method for acute kidney injury detection in ELBW neonates.

Mathilde Dumoulin Hans Pottel Djalila Mekahli Annouschka Laenen Anne Smits Karel Allegaert

Published in: Pediatric nephrology (Berlin, Germany) (2024)

As rescaled Scr biomarker, the Pottel method showed a clear association with ibuprofen-exposed ELBW neonates, suggesting its applicability as a pragmatic bedside alternative tool to assess nephrotoxicity.

Keyphrases

acute kidney injury
low birth weight
drug induced
cardiac surgery
preterm infants
adverse drug
preterm birth
study protocol
clinical trial
randomized controlled trial
emergency department
real time pcr
electronic health record
double blind